Prognostic Impact of Lymphocyte-C-Reactive Protein Ratio in Patients Who Underwent Surgical Resection for Hepatocellular Carcinoma
| Autor: | Keitaro Edahiro, Takuro Kometani, Kozo Konishi, Nao Kinjo, Takahiro Omine, Koto Kawata, Shinichiro Ikeda, Shinichi Tsutsui, Hiroyuki Matsuda, Makoto Edagawa, Kyohei Yugawa, Shohei Yamaguchi, Takashi Maeda |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Carcinoma Hepatocellular Lymphocyte urologic and male genital diseases Gastroenterology Internal medicine medicine Humans Lymphocytes Retrospective Studies Prothrombin time biology medicine.diagnostic_test business.industry C-reactive protein Hazard ratio Liver Neoplasms Retrospective cohort study medicine.disease Prognosis female genital diseases and pregnancy complications Confidence interval medicine.anatomical_structure C-Reactive Protein Hepatocellular carcinoma biology.protein Surgery business |
| Zdroj: | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 26(1) |
| ISSN: | 1873-4626 |
| Popis: | Systemic inflammation-related factors, either independently or in combination, are recognized as prognostic factors for various cancers. The ratio of lymphocyte count to C-reactive protein concentration (lymphocyte–CRP ratio; LCR) is a recently identified prognostic marker for several cancers. Here, we examined the prognostic value of the LCR in patients with hepatocellular carcinoma (HCC). This was a single-center retrospective study of patients who underwent surgical resection for HCC between 2004 and 2017. Patients were divided into high- and low-LCR status groups, and the relationships between LCR status, prognosis, and other clinicopathological characteristics were analyzed. A total of 454 patients with HCC were enrolled and assigned to the high- (n=245) or low- (n=209) LCR groups. Compared with the high-LCR group, patients in the low-LCR group had a significantly lower serum albumin level (median 4.1 vs. 3.9 g/dL, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink