Functional imaging equivalence and proof of concept for image-guided adaptive radiotherapy with fixed gantry and rotating couch
| Autor: | David Stewart, Paul F. White, Paul J. Keall, Ricky O'Brien, Brendan Whelan, Siddhartha Baxi, Peter Lazarakis, Chen-Yu Huang, William Counter, Michael Barton, Kuldeep Makhija, Michael Jackson, Ilana Feain, Chun-Chien Shieh, Sandra Fisher, Simon Downes |
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| Rok vydání: | 2016 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
Cone beam computed tomography lcsh:R895-920 Physics::Medical Physics Image registration Iterative reconstruction lcsh:RC254-282 Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Medicine Scientific Article Radiology Nuclear Medicine and imaging Computer vision Equivalence (measure theory) Ground truth business.industry lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Compressed sensing Transformation (function) Oncology Computer Science::Computer Vision and Pattern Recognition 030220 oncology & carcinogenesis Artificial intelligence business |
| Zdroj: | Advances in Radiation Oncology Advances in Radiation Oncology, Vol 1, Iss 4, Pp 365-372 (2016) |
| ISSN: | 2452-1094 |
| Popis: | Purpose: The purpose of this article is to present the first imaging experiments to demonstrate the functional equivalence between a conventional rotational gantry and a fixed-beam imaging geometry, and the feasibility of an iterative image-reconstruction technique under gravitational deformation. Methods and materials: Experiments were performed using an Elekta Axesse with Agility MLC and XVI, a custom-built rotating phantom stage, a Catphan QA phantom, and a porcine heart. For the imaging equivalence, a conventional cone beam computed tomography (CBCT) of the Catphan was acquired, as well as a set of 660 x-ray projections with a static gantry and rotating Catphan. Both datasets were reconstructed with the Feldkamp-Davis-Kress (FDK) algorithm, and the resultant volumetric images were compared using standard metrics. For imaging under gravitational deformation, a conventional CBCT of the Catphan and a set of 660 x-ray projections with a static gantry and rotating Catphan were also acquired with a porcine heart. The conventional CBCT was reconstructed using FDK. The projections that were acquired with the heart rotating were sorted into angular bins and reconstructed with prior image constrained compressed sensing using a deformation-blurred FDK prior. Deformation was quantified with B-spline transformation-based deformable image registration. Results: For imaging equivalence, the difference between the two Catphan images was consistent with Poisson noise. For imaging under gravitational deformation, the conventional CBCT porcine heart image (ground truth at 0 degrees) matched the static gantry, rotating heart reconstruction with a mean magnitude of |
| Databáze: | OpenAIRE |
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