Evolution of Volume and Signal Intensity on Fluid-attenuated Inversion Recovery MR Images after Endovascular Stroke Therapy
| Autor: | Brannon Cha, Greg Zaharchuk, Soren Christensen, Maarten G Lansberg, Michael Mlynash, Christian Federau, Max Wintermark, Gregory W. Albers |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Perfusion scanning Fluid-attenuated inversion recovery Severity of Illness Index Lesion 03 medical and health sciences symbols.namesake 0302 clinical medicine Statistical significance medicine Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Prospective Studies Prospective cohort study Stroke Fisher's exact test Aged Thrombectomy medicine.diagnostic_test business.industry Endovascular Procedures Brain Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging Treatment Outcome symbols Female Radiology medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Radiology. 280(1) |
| ISSN: | 1527-1315 |
| Popis: | Purpose To analyze both volume and signal evolution on magnetic resonance (MR) fluid-attenuated inversion recovery (FLAIR) images between the images after endovascular therapy and day 5 (which was the prespecified end point for infarct volume in the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution [DEFUSE 2] trial) in a subset of patients enrolled in the DEFUSE 2 study. Materials and Methods This study was approved by the local ethics committee at all participating sites. Informed written consent was obtained from all patients. In this post hoc analysis of the DEFUSE 2 study, 35 patients with FLAIR images acquired both after endovascular therapy (median time after symptom onset, 12 hours) and at day 5 were identified. Patients were separated into two groups based on the degree of reperfusion achieved on time to maximum greater than 6-second perfusion imaging (≥90% vs |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|