Opposite effect of motivated forgetting on sleep spindles during stage 2 and slow wave sleep
| Autor: | Mostafa Safaie, Sahar Moghimi, Shima Sadrabadi Haghighi, Maryam Ghorbani, Fereshteh Dehnavi |
|---|---|
| Přispěvatelé: | Ferdowsi University of Mashhad (FUM), Institut de Neurobiologie de la Méditerranée [Aix-Marseille Université] (INMED - INSERM U1249), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), DESSAIVRE, Louise |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty [SDV]Life Sciences [q-bio] Sleep spindle Electroencephalography Audiology Sleep Slow-Wave 03 medical and health sciences Young Adult stage 2 sleep 0302 clinical medicine motivated forgetting Physiology (medical) mental disorders medicine Humans Learning slow wave sleep 030304 developmental biology Slow-wave sleep 0303 health sciences Motivation medicine.diagnostic_test Recall Recall test Motivated forgetting sleep spindles [SDV] Life Sciences [q-bio] Nap Memory Short-Term Mental Recall Female Neurology (clinical) Sleep (system call) Cues Psychology psychological phenomena and processes 030217 neurology & neurosurgery |
| Zdroj: | SLEEP SLEEP, Oxford University Press 2019, 42 (7), ⟨10.1093/sleep/zsz085⟩ SLEEP, 2019, 42 (7), ⟨10.1093/sleep/zsz085⟩ |
| ISSN: | 1550-9109 0161-8105 |
| Popis: | Memories selectively benefit from sleep. In addition to the importance of the consolidation of relevant memories, the capacity to forget unwanted memories is also crucial. We investigated the effect of suppressing unwanted memories on electroencephalography activity of subsequent sleep using a motivated forgetting (MF) paradigm as compared with a control non-forgetting task. Subjects were randomly assigned to nap or no-nap groups. We used a modified version of the think/no-think paradigm with dominant number of no-think words cued to be forgotten and included only subjects capable of suppressing unwanted memories by performing an initial subject inclusion experiment. In both groups and conditions, the performance of the subjects in recalling the word pairs learned in the beginning of the day was evaluated in a final recall test. We found that both nap and no-nap groups recalled significantly less no-think words in the MF condition compared to the control condition. Moreover, for the nap group, in the MF compared to the control condition, spindle power and density increased during stage 2 (S2) whereas they decreased during slow wave sleep (SWS). Interestingly, recall performance of no-think words was negatively correlated with spindle power during S2 whereas it was positively correlated with spindle power during SWS. These results indicate that sleep spindles are sensitive to the previous MF experiences and suggest a differential role of sleep spindles during S2 and SWS in memory processing during sleep. |
| Databáze: | OpenAIRE |
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