Differential activation of the human costal and crural diaphragm during voluntary and involuntary breaths
| Autor: | Simon C. Gandevia, Anna L. Hudson, Jane E. Butler, Euan J. McCaughey, David A. T. Nguyen, Nasim Amirjani |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Leg medicine.diagnostic_test Electromyography Physiology business.industry Respiration Diaphragm Anatomy musculoskeletal system Diaphragm (structural system) Hypercapnia 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Physiology (medical) Breathing Animals Humans Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Applied Physiology. 128:1262-1270 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/japplphysiol.00790.2019 |
| Popis: | The diaphragm is the primary muscle that generates the negative intrathoracic pressure to drive inspiratory airflow. The diaphragm consists of two parts, the costal and crural portions, with different roles during inspiration in animals, particularly when the stimulus to breathe is increased. In this study, the neural drive to the costal and crural portions of the diaphragm was assessed in nine healthy participants [8 male, aged 32 ± 13 yr (mean ± SD)]. Inspiratory electromyographic activity (EMG) was recorded from the costal diaphragm by using an intramuscular electrode and from the crural diaphragm with a multipair gastroesophageal catheter. Participants performed voluntary augmented breaths at 120%, 140%, and 160% of their tidal volume and also underwent progressive hypercapnia to induce involuntary breathing. Irrespective of the task, the increase in crural activity (normalized to quiet breathing) was only ~60% of the increase in costal activity (slope: 0.56 ± 0.30 |
| Databáze: | OpenAIRE |
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