Comparison of Outcomes Between Transperitoneal and Retroperitoneal Robotic Partial Nephrectomy: A Meta-Analysis Based on Comparative Studies
Autor: | Liangyou Gu, Taoping Shi, Daqing Zhu, Yi Wang, Xue Shao, Nandong Zhang, Gang Guo |
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Rok vydání: | 2021 |
Předmět: |
Cancer Research
medicine.medical_specialty Funnel plot partial nephrectomy medicine.medical_treatment 030232 urology & nephrology Urology Cochrane Library lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine Blood loss kidney neoplasms Medicine robotics business.industry Odds ratio Publication bias Perioperative lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Nephrectomy meta-analysis Oncology 030220 oncology & carcinogenesis Meta-analysis outcome Systematic Review business |
Zdroj: | Frontiers in Oncology Frontiers in Oncology, Vol 10 (2021) |
ISSN: | 2234-943X |
Popis: | BackgroundTo compare perioperative, functional and oncological outcomes between transperitoneal robotic partial nephrectomy (TRPN) and retroperitoneal robotic partial nephrectomy (RRPN).MethodsA literature searching of Pubmed, Embase, Cochrane Library and Web of Science was performed in August, 2020. Pooled odds ratios (ORs) or weighted mean differences (WMDs) with 95% confidence intervals (CIs) were estimated using fixed-effect or random-effect model. Publication bias was evaluated with funnel plots. Only comparative studies with matched design or similar baseline characteristics were included.ResultsEleven studies embracing 2,984 patients were included. There was no significant difference between the two groups regarding conversion to open (P = 0.44) or radical (P = 0.31) surgery, all complications (P = 0.06), major complications (P = 0.07), warm ischemia time (P = 0.73), positive surgical margin (P = 0.87), decline in eGFR (P = 0.42), CKD upstaging (P = 0.72), and total recurrence (P = 0.66). Patients undergoing TRPN had a significant higher minor complications (P = 0.04; OR: 1.39; 95% CI, 1.01–1.91), longer operative time (P < 0.001; WMD: 21.68; 95% CI, 11.61 to 31.76), more estimated blood loss (EBL, P = 0.002; WMD: 40.94; 95% CI, 14.87 to 67.01), longer length of hospital stay (LOS, P < 0.001; WMD: 0.86; 95% CI, 0.35 to 1.37). No obvious publication bias was identified.ConclusionRRPN is more favorable than TRPN in terms of less minor complications, shorter operative time, less EBL, and shorter LOS. Methodological limitations of the included studies should be considered while interpreting these results. |
Databáze: | OpenAIRE |
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