Symptom combinations assessed in traditional Chinese medicine and its predictive role in ACR20 efficacy response in rheumatoid arthritis
| Autor: | Yinglin Zha, Cheng Lu, Xiaoping Yan, Li Su, Aiping Lu, Xinghua Feng, Yuejin Song, Ian Tsang, Xian Qian, Shengping Zeng, Wei Liu, Yiting He, Wanhua Zhu |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization Adolescent Tripterygium Traditional Chinese medicine Severity of Illness Index Arthritis Rheumatoid Rheumatology Predictive Value of Tests Internal medicine medicine Humans In patient Single-Blind Method Medicine Chinese Traditional Aged Complete physical examination business.industry Anti-Inflammatory Agents Non-Steroidal General Medicine Middle Aged medicine.disease Treatment Outcome Complementary and alternative medicine Rheumatoid arthritis Antirheumatic Agents Physical therapy Female business Western medicine Drugs Chinese Herbal |
| Zdroj: | The American journal of Chinese medicine. 36(4) |
| ISSN: | 0192-415X |
| Popis: | The predictive roles of symptom combination traditionally evaluated in traditional Chinese medicine (TCM) in the treatment of rheumatoid arthritis (RA) were explored. Three hundred and ninety six patients were randomly divided into 197 subjects receiving Western medicine therapy (WM) and 199 subjects receiving TCM therapy (TCM). A complete physical examination and 18 clinical manifestations typically assessed in TCM were recorded before the randomization. The ACR responses were used for efficacy evaluation. ACR20 and 50 responses with WM treatment were higher than in the TCM group. The 18 symptoms in RA could be clustered into 4 symptom combinations with factor analysis, which represent joint symptoms, cold pattern, deficiency pattern and hot pattern in TCM respectively. TCM would be more effective in patients with weak-symptom combination 3 (deficiency pattern in TCM), and WM would be more effective in patients with symptom combination 2 (cold pattern in TCM). Symptom combinations judged with TCM may have influence on the efficacy of therapy in the treatment of RA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|