Straightforward Immobilization of Phosphonic Acids and Phosphoric Acid Esters on Mesoporous Silica and Their Application in an Asymmetric Aldol Reaction
| Autor: | René Wilhelm, Heinrich Marsmann, Patrick Schnippering, Anpeng Guo, Claudia Schmidt, Christian Weinberger, Tatjana Heckel, Waldemar Keil, Michael Tiemann, Markus Schmitz |
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| Rok vydání: | 2019 |
| Předmět: |
General Chemical Engineering
magic-angle spinning NMR (MAS-NMR) Mesoporous silica Toluene Article Catalysis lcsh:Chemistry Solvent chemistry.chemical_compound lcsh:QD1-999 chemistry Aldol reaction Azeotropic distillation Organocatalysis Organic chemistry organocatalysis General Materials Science mesoporous silica host–guest materials Mesoporous material |
| Zdroj: | Nanomaterials Volume 9 Issue 2 Nanomaterials, Vol 9, Iss 2, p 249 (2019) |
| ISSN: | 2079-4991 |
| DOI: | 10.3390/nano9020249 |
| Popis: | The combined benefits of moisture-stable phosphonic acids and mesoporous silica materials (SBA-15 and MCM-41) as large-surface-area solid supports offer new opportunities for several applications, such as catalysis or drug delivery. We present a comprehensive study of a straightforward synthesis method via direct immobilization of several phosphonic acids and phosphoric acid esters on various mesoporous silicas in a Dean&ndash Stark apparatus with toluene as the solvent. Due to the utilization of azeotropic distillation, there was no need to dry phosphonic acids, phosphoric acid esters, solvents, or silicas prior to synthesis. In addition to modeling phosphonic acids, immobilization of the important biomolecule adenosine monophosphate (AMP) on the porous supports was also investigated. Due to the high surface area of the mesoporous silicas, a possible catalytic application based on immobilization of an organocatalyst for an asymmetric aldol reaction is discussed. |
| Databáze: | OpenAIRE |
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