Effects of Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in mice
| Autor: | María Alejandra Córdoba, Valeria Fernanda Del Coco, Juan Ángel Basualdo, Mónica Santín, Mónica Sparo, Alicia Sidoti |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty animal diseases 030106 microbiology Cryptosporidiosis Cryptosporidium Enterococcus faecalis law.invention Microbiology Enterococcus faecalis CECT7121 03 medical and health sciences Probiotic Immunocompromised Host Mice Medical microbiology Intestinal mucosa law Immunosuppressed mice parasitic diseases medicine Animals Humans Intestinal Mucosa Cryptosporidium parvum General Veterinary biology Antiparasitic Agents Probiotics General Medicine biology.organism_classification Antiparasitic agent Disease Models Animal Infectious Diseases Insect Science Immunology Ciencias Médicas Protozoa Parasitology |
| Zdroj: | SEDICI (UNLP) Universidad Nacional de La Plata instacron:UNLP |
| Popis: | Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection. Facultad de Ciencias Médicas Facultad de Ciencias Exactas Comisión de Investigaciones Científicas de la provincia de Buenos Aires Centro Universitario de Estudios Microbiológicos y Parasitológicos |
| Databáze: | OpenAIRE |
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