Association between CYP2A13 polymorphisms and lung cancer
| Autor: | Hongyi Zhang, Jiawei Liu, Wenhao Wang, Yao Pang, Long Ma, Gang Jin, Peng Wu, Kui Wang, Jialong Li, Zequan Wang, Yi Yang, Ruitong Chang, Zijiang Zhu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Oncology
medicine.medical_specialty Lung Neoplasms MEDLINE Cochrane Library polymorphism 03 medical and health sciences 0302 clinical medicine Internal medicine Study Protocol Systematic Review medicine Humans Genetic Predisposition to Disease 030212 general & internal medicine Lung cancer Polymorphism Genetic business.industry General Medicine Odds ratio medicine.disease Lung cancer susceptibility Confidence interval meta-analysis lung cancer cytochrome P450 2A13 CYP2A13 030220 oncology & carcinogenesis Meta-analysis Aryl Hydrocarbon Hydroxylases business Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 2020-9010 |
| DOI: | 10.1097/md.0000000000023289 |
| Popis: | Background: Recently, lung cancer has become the most common cause of cancer-related death, several studies indicate that the cytochrome P450 2A13 (CYP2A13) polymorphisms may be correlated with lung cancer susceptibility, but the results have been inconsistent and inconclusive. Therefore, the aim of this meta-analysis is to provide a precise conclusion on the potential association between CYP2A13 polymorphisms and the risk of lung cancer based on case-control studies. Methods: The PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Infrastructure (CNKI) databases will be searched for case-control studies published up to September 2020. Odds ratio (OR) and 95% confidence interval (95% CI) were used to determine the effects of the CYP2A13 polymorphism on lung cancer risk, respectively. Results: The results of this meta-analysis will be submitted to a peer-reviewed journal for publication. Conclusion: This meta-analysis will summarize the association between CYP2A13 polymorphisms and the risk of lung cancer. INPLASY registration number: INPLASY202090102 |
| Databáze: | OpenAIRE |
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