Effect of gamma irradiation on phenol content, antioxidant activity and biological activity of black maca and red maca extracts (Lepidium meyenii walp)
| Autor: | C Vasquez, Alisson Zevallos-Concha, Manuel Gasco, D Nuñez, M Quispe, Gustavo F. Gonzales |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Antioxidant Lepidium/chemistry DPPH Ultraviolet Rays Health Toxicology and Mutagenesis medicine.medical_treatment Toxicology red maca Lepidium Antioxidants chemistry.chemical_compound Mice 0404 agricultural biotechnology Phenols medicine Phenol Plant Extracts/chemistry/pharmacology Animals Antioxidants/chemistry/pharmacology Testosterone polyphenols purl.org/pe-repo/ocde/ford#3.01.07 [https] Lepidium meyenii Traditional medicine black maca Phenols/chemistry Plant Extracts Spectrophotometry Atomic Biological activities radical-scavenging activities Biological activity 04 agricultural and veterinary sciences 040401 food science gamma irradiation chemistry Polyphenol Gamma Rays Female Gamma irradiation |
| Zdroj: | Toxicology mechanisms and methods. 26(1) |
| ISSN: | 1537-6524 |
| Popis: | This study was performed to determine the effects of gamma irradiation on UV spectrum on maca, total content of polyphenols, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activities and in vivo biological activities of red and black maca extracts (Lepidium meyenii). Adult mice of the strain Swiss aged 3 months and weighing 30-35 g in average were used to determine biological activities. Daily sperm production, effect on testosterone-induced prostate hyperplasia and forced swimming test were used to determine the effect of irradiation on biological activities of maca extracts. Irradiation did not show differences in UV spectrum but improves the amount of total polyphenols in red maca as well as in black maca extracts. In both cases, black maca extract has more content of polyphenols than red maca extract (p < 0.01). Gamma irradiation significantly increased the antioxidant capacity (p < 0.05). No difference was observed in daily sperm production when irradiated and nonirradiated maca extract were administered to mice (p > 0.05). Black maca extract but not red maca extract has more swimming endurance capacity in the forced swimming test. Irradiation of black maca extract increased the swimming time to exhaustion (p < 0.05). This is not observed with red maca extract (p > 0.05). Testosterone enanthate (TE) increased significantly the ventral prostate weight. Administration of red maca extract in animals treated with TE prevented the increase in prostate weight. Irradiation did not modify effect of red maca extract on prostate weight (p > 0.05). In conclusion, irradiation does not alter the biological activities of both black maca and red maca extracts. It prevents the presence of microorganisms in the extracts of black or red maca, but the biological activities were maintained. |
| Databáze: | OpenAIRE |
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