A Rare Coexistence of Medullary Thyroid Cancer with Graves Disease: A Case Report and Systematic Review of the Literature
| Autor: | Anastasios Papanastasiou, Konstantinos Sapalidis, Dimitrios Giannakidis, Georgios Koimtzis, Stylianos Mantalovas, Christos Poulios, Maria Florou, Niki Mantha, Nikolaos V. Michalopoulos, Isaak Kesisoglou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty endocrine system Medullary cavity endocrine system diseases medicine.medical_treatment Graves' disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine medicine Humans Euthyroid Thyroid Neoplasms Thyroid cancer Incidental Findings business.industry Thyroid Thyroidectomy Medullary thyroid cancer General Medicine Articles medicine.disease eye diseases Graves Disease Carcinoma Neuroendocrine Carbimazole medicine.anatomical_structure 030220 oncology & carcinogenesis Carcinoma Medullary business medicine.drug |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Patient: Male, 39 Final Diagnosis: Medullary thyroid cancer Symptoms: Hyperthyroidism symptoms Medication: — Clinical Procedure: Total thyroidectomy Specialty: Surgery Objective: Rare disease Background: Graves disease is occasionally associated with thyroid cancer. The most common histological type of thyroid cancer in patients with Graves disease is papillary followed by follicular. Medullary thyroid cancer and Graves disease have been reported simultaneously only in a few cases in the literature. Case Report: A case of coexistence of Graves disease and medullary thyroid cancer is described in this report. The patient was diagnosed with Graves disease 8 years ago. Although he had an initial successful treatment with carbimazole, in the last 2 years no steady euthyroid function was achieved. Total thyroidectomy was considered as the optimal treatment. An incidental medullary microcarcinoma with maximum diameter 0.5 cm was identified by pathology report. Conclusions: Medullary thyroid cancer has been reported in patients with Graves disease in 15 cases, including the current case. Medullary thyroid cancer is aggressive, and a delayed diagnosis would be harmful. Hence, patients with Graves disease should be evaluated regularly by a thyroid specialist. |
| Databáze: | OpenAIRE |
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