Investigation of an Outbreak of Hepatitis A in Irish Haemophilia A Patients
Autor: | I. J. Temperley, Z. Johnson, E. Lawlor, L. Thornton |
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Rok vydání: | 1994 |
Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty business.industry Transmission (medicine) Haemophilia A Outbreak Hepatitis A Serological evidence Hematology General Medicine medicine.disease language.human_language Irish Immunology language Medicine business |
Zdroj: | Vox Sanguinis. 67:18-20 |
ISSN: | 1423-0410 0042-9007 |
DOI: | 10.1111/j.1423-0410.1994.tb00968.x |
Popis: | Since 1990, Irish haemophilia A patients have been treated with solvent-detergent(SD)-treated virally inactivated high-purity factor VIII concentrate prepared from plasma from Irish voluntary non-remunerated donors. In 1992, 13 haemophilia A patients developed clinical hepatitis A and a further 17 patients showed serological evidence of recent infection by hepatitis A. All but 3 of these patients had had recent exposure to SD-treated product. A case-control study is underway to determine whether these cases represent transmission through product or environmentally acquired hepatitis A. |
Databáze: | OpenAIRE |
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