Investigation of an Outbreak of Hepatitis A in Irish Haemophilia A Patients

Autor: I. J. Temperley, Z. Johnson, E. Lawlor, L. Thornton
Rok vydání: 1994
Předmět:
Zdroj: Vox Sanguinis. 67:18-20
ISSN: 1423-0410
0042-9007
DOI: 10.1111/j.1423-0410.1994.tb00968.x
Popis: Since 1990, Irish haemophilia A patients have been treated with solvent-detergent(SD)-treated virally inactivated high-purity factor VIII concentrate prepared from plasma from Irish voluntary non-remunerated donors. In 1992, 13 haemophilia A patients developed clinical hepatitis A and a further 17 patients showed serological evidence of recent infection by hepatitis A. All but 3 of these patients had had recent exposure to SD-treated product. A case-control study is underway to determine whether these cases represent transmission through product or environmentally acquired hepatitis A.
Databáze: OpenAIRE