Diagnostic value of post-bronchodilator pulmonary function testing to distinguish between stable, moderate to severe COPD and asthma
| Autor: | J. R. Joubert, Macé M. Schuurmans, Elvis M Irusen, Haylene Nell, Daphne C Richter |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Spirometry
Male medicine.medical_specialty Vital capacity diagnosis Vital Capacity International Journal of Chronic Obstructive Pulmonary Disease Sensitivity and Specificity Severity of Illness Index Pulmonary function testing Diagnosis Differential FEV1/FVC ratio Pulmonary Disease Chronic Obstructive Predictive Value of Tests Internal medicine Forced Expiratory Volume Administration Inhalation medicine obstructive lung disease Humans Albuterol Prospective Studies Asthma Original Research lcsh:RC705-779 COPD medicine.diagnostic_test business.industry lcsh:Diseases of the respiratory system General Medicine respiratory system Middle Aged medicine.disease post-bronchodilator pulmonary function test Obstructive lung disease respiratory tract diseases Bronchodilator Agents Respiratory Function Tests Predictive value of tests Cardiology Physical therapy Female business |
| Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease Scopus-Elsevier International Journal of COPD, Vol 2008, Iss Issue 4, Pp 693-699 (2008) |
| ISSN: | 1178-2005 1176-9106 |
| Popis: | Daphne C Richter1, James R Joubert1, Haylene Nell1, Mace M Schuurmans2, Elvis M Irusen21Tiervlei Trial Centre, Karl Bremer Hospital, Bellville, RSA; 2Respiratory Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of Stellenbosch, RSAObjective: The GOLD guidelines suggest that the presence of a post-bronchodilator forced expiratory volume in one second (FEV1) 80% of the predicted value in combination with a FEV1/forced vital capacity (FVC)< 70% confirms the diagnosis of COPD. Limited data exist regarding the accuracy of these criteria to distinguish between COPD and asthma. The aim of this study therefore was to investigate the diagnostic value of post-bronchodilator lung function parameters in obstructive lung disease.Methods: The pulmonary function tests of 43 (22 = COPD, 21 = asthma) patients with similar baseline characteristics were evaluated (baseline FEV1 were 55.7% + 7.6%, and 59.3% + 8.4% predicted for COPD and asthma, respectively). Bronchodilator responsiveness (BDR) was calculated according to three recognized pulmonary function test criteria.Results: The first criteria, post-bronchodilator FEV1< 80% of the predicted value in combination with a post-bronchodilator FEV1/FVC ratio of |
| Databáze: | OpenAIRE |
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