Noninvasive Ventilation Accelerates Oxygen Uptake Recovery Kinetics in Patients With Combined Heart Failure and Chronic Obstructive Pulmonary Disease
| Autor: | Priscila A. Sperandio, Flavio F. Arbex, Cássia da Luz Goulart, Aline Soares de Souza, Audrey Borghi-Silva, Maria Clara Alencar, Adriana Mazzuco, Ross Arena, José Alberto Neder, Wladimir M. Medeiros |
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| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Cardiac output medicine.medical_specialty 030204 cardiovascular system & hematology Work rate Ventricular Function Left 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Oxygen Consumption Internal medicine Heart rate medicine Humans In patient Heart Failure COPD Exercise Tolerance Noninvasive Ventilation Cardiopulmonary rehabilitation business.industry Rehabilitation Stroke Volume medicine.disease Oxygen Kinetics 030228 respiratory system Heart failure Breathing Cardiology Exercise Test Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of cardiopulmonary rehabilitation and prevention. 40(6) |
| ISSN: | 1932-751X |
| Popis: | PURPOSE Oxygen uptake (V˙o2) recovery kinetics appears to have considerable value in the assessment of functional capacity in both heart failure (HF) and chronic obstructive pulmonary disease (COPD). Noninvasive positive pressure ventilation (NIPPV) may benefit cardiopulmonary interactions during exercise. However, assessment during the exercise recovery phase is unclear. The purpose of this investigation was to explore the effects of NIPPV on V˙o2, heart rate, and cardiac output recovery kinetics from high-intensity constant-load exercise (CLE) in patients with coexisting HF and COPD. METHODS Nineteen males (10 HF/9 age- and left ventricular ejection fraction-matched HF-COPD) underwent 2 high-intensity CLE tests at 80% of peak work rate to the limit of tolerance (Tlim), receiving either sham ventilation or NIPPV. RESULTS Despite greater V˙o2 recovery kinetics on sham, HF-COPD patients presented with a faster exponential time constant τ (76.4 ± 14.0 sec vs 62.8 ± 15.2 sec, P < .05) and mean response time (MRT) (86.1 ± 19.1 sec vs 68.8 ± 12.0 sec, P < .05) with NIPPV and greater ΔNIPPV-sham (τ: 5.6 ± 19.5 vs -25.2 ± 22.4, P < .05; MRT: 4.1 ± 32.2 vs -26.0 ± 19.2, P < .05) compared with HF. There was no difference regarding Tlim between sham and NIPPV in both groups (P < .05). CONCLUSION Our results suggest that NIPPV accelerated the V˙o2 recovery kinetics following high-intensity CLE to a greater extent in patients with coexisting HF and COPD compared with HF alone. NIPPV should be considered when the objective is to apply high-intensity interval exercise training as an adjunct intervention during a cardiopulmonary rehabilitation program. |
| Databáze: | OpenAIRE |
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