| Autor: |
Ashwin A. Seshia, Angel T.-H. Lin, Jize Yan |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Procedia Engineering. 5:1454-1457 |
| ISSN: |
1877-7058 |
| DOI: |
10.1016/j.proeng.2010.09.390 |
| Popis: |
The adaptation of micro- and nanomechanical resonators as mass balances for biochemical sensing has received much attention in recent years due to the potential for very high resolution and electrical readout of target analyte in a label-free format. However, several implementation challenges arise from the necessity of operation in compatible biological buffer solutions. These challenges include minimizing undesired effects of fluid-structure interaction and buffer interference with signal transduction. Electrical readout of the sensor response is complicated by coupling to the electrical properties of the buffer solution and voltage limitations due to the possibility of undesired electrochemical reactions on the sensor surface. To address this problem we propose a novel dual resonator platform, wherein electrical transduction and sensing are spatially separated onto two different mechanically coupled resonators. In this work, we demonstrate the functionality of the dual resonator system as a mass sensing platform, with a mass responsivity of 37 Hz/ng. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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