Study of cutaneous melanoma recurrences after sentinel node biopsy: Patterns of dissemination and use of complementary test in follow-up
Autor: | Maria José Lecumberri-Biurrun, Juan Ignacio Yanguas-Bayona, Imanol Arozarena-Martinicorena, Elena Goñi-Gironés, Leire Loidi-Pascual |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Skin Neoplasms Sentinel lymph node Metastasis Breslow Thickness 03 medical and health sciences 0302 clinical medicine Medicine Humans Stage (cooking) Melanoma Neoplasm Staging Retrospective Studies business.industry Sentinel Lymph Node Biopsy Retrospective cohort study Sentinel node medicine.disease Oncology 030220 oncology & carcinogenesis Lymphatic Metastasis Cutaneous melanoma Radiology Neoplasm Recurrence Local business Follow-Up Studies |
Zdroj: | European journal of cancer careREFERENCES. 30(1) |
ISSN: | 1365-2354 |
Popis: | OBJECTIVES To investigate the patterns of melanoma recurrence in the local population, including factors that may influence in this event and timing of relapse, and to determine the mode of detection of them. METHODS This is a retrospective cohort study of patients with melanoma who underwent sentinel lymph node biopsy at the Complejo Hospitalario de Navarra (Spain) from 2002 to 2012. The following data were collected of each patient: age, gender, date of diagnosis, location of melanoma, histological subtype, Breslow thickness, ulceration, mitosis, sentinel node status, AJCC 8th edition stage, site of first diagnosed metastasis, mode of relapse, date of first relapse and time of death. RESULTS Of 308 patients, 30% people suffered metastasis. The mean follow-up time was 68.63 months. 51.1% of relapses were locoregional and 48.9% haemato-visceral. Sentinel node status was the only variable associated with higher risk of haemato-visceral metastasis (p |
Databáze: | OpenAIRE |
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