Polymicrobial vertebral osteomyelitis after oesophageal biopsy
| Autor: | Erlangga Yusuf, Olivier Clerc, Aude Giger, Oriol Manuel, Andrej Trampuz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
Spondylodiscitis medicine.medical_specialty Mixed infections Antifungal Agents Pathologic fracture Streptococcus mitis Case Report Gemella morbillorum 600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit Thoracic Vertebrae 03 medical and health sciences 0302 clinical medicine Candida albicans Gemella medicine Carcinoma Back pain Humans Vertebral osteomyelitis 030212 general & internal medicine Abscess Aged 030203 arthritis & rheumatology biology business.industry Anti-Bacterial Agents/therapeutic use Antifungal Agents/therapeutic use Candida albicans/isolation & purification Gemella/isolation & purification Magnetic Resonance Imaging Osteomyelitis/diagnosis Osteomyelitis/drug therapy Spine/radiography Streptococcus mitis/isolation & purification Thoracic Vertebrae/microbiology Osteomyelitis medicine.disease biology.organism_classification Spine Anti-Bacterial Agents Surgery Radiography Postinterventional osteomyelitis medicine.anatomical_structure Infectious Diseases Thoracic vertebrae medicine.symptom business |
| Zdroj: | Bmc Infectious Diseases, vol. 16, no. 1, pp. 141 BMC Infectious Diseases |
| DOI: | 10.17169/refubium-18410 |
| Popis: | BACKGROUND: While most cases of polymicrobial vertebral osteomyelitis are secondary to hematogenous seeding, direct inoculation during spinal surgery and contiguous spread from adjacent soft tissue are also potential routes whereby pathogens may infect the spine. CASE PRESENTATION: A 74 year-old man presented with an exacerbation of back pain after a fall. His past medical history included hepatocellular and oesophageal carcinoma. Three months earlier he had undergone an endoscopic biopsy of the oesophagus for routine follow-up of his oesophagus carcinoma. He also underwent a vertebroplasty due to suspected pathologic fracture. On admission to hospital, magnetic resonance imaging revealed an infiltrative process at the level of the 5th and 6th thoracic vertebrae. Blood cultures were positive for both Streptococcus mitis and Gemella morbillorum. During his course of antibiotic therapy he developed an abscess at the level of 8th thoracic vertebrae and culture of this abscess grew Candida albicans. He was treated with antibiotics and antifungal drugs and recovered fully. CONCLUSION: Vertebral osteomyelitis may be caused by direct spread following an oesophageal procedure. Microbiological diagnosis is essential to target the specific pathogen, especially in cases of polymicrobial infection. |
| Databáze: | OpenAIRE |
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