Propranolol in the treatment of migraine
Autor: | Tor-Erik Widerøe, Tor Vigander |
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Rok vydání: | 1974 |
Předmět: |
Male
Migraine Disorders Respiratory Tract Diseases Propranolol Placebo Common migraine law.invention Placebos Randomized controlled trial law medicine Humans General Environmental Science Clinical Trials as Topic business.industry Respiration General Engineering General Medicine Papers and Originals Mean frequency medicine.disease Clinical trial Migraine Anesthesia General Earth and Planetary Sciences Female business medicine.drug |
Zdroj: | British medical journal. 2(5921) |
ISSN: | 0007-1447 |
Popis: | Beta-blocking drugs that prevent cranial vasodilatation are potentially valuable in the prophylaxis of migraine. Forty-nine patients with either classic or common migraine were treated with propranolol 160 mg/day for an average of six months. The first 30 of the patients to respond well to this treatment then participated in a double-blind cross-over trial with a placebo and propranolol. The mean frequency of headache attacks was significantly reduced by propranolol. None of the patients expressed a preference for placebo. Propranolol seems to be an effective prophylactic for common and classic migraine but the antimigraine properties of the various beta-blocking agents probably differ. |
Databáze: | OpenAIRE |
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