Inducing achiral aliphatic oligoureas to fold into helical conformations

Autor:	Romina Wechsel, Julien Maury, Juliette Fremaux, Scott P. France, Gilles Guichard, Jonathan Clayden
Rok vydání:	2014
Předmět:	chemistry.chemical_compound Monomer Chemistry Stereochemistry Materials Chemistry Metals and Alloys Ceramics and Composites Trimer General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Chiral diamine
Zdroj:	Chemical communications (Cambridge, England). 50(95)
ISSN:	1364-548X
Popis:	The ability of urea-linked oligomers of achiral diamines (achiral analogues of the well-established chiral oligourea foldamers) to adopt helical conformations was explored spectroscopically. Up to four achiral units were ligated either to a well-formed helical trimer or to a single chiral diamine, and the extent to which they adopted a screw-sense preference was determined by NMR and CD. In the best performing cases, a trimeric chiral oligourea and even a single cis-cyclohexanediamine monomer induced folding into a helical conformation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f371dda187f4dbbf5f530b9774390f8e https://pubmed.ncbi.nlm.nih.gov/25327885 Zobrazit plný text záznamu