Splenic switch-off, a potential novel marker of lack of adenosine response: prevalence and measurement reproducibility
| Autor: | Mark Westwood, Charlotte Manisty, Steffen E. Petersen, Ian S Stone, Alice Lighton, Ceri Davies, Neha Sekhri, Mohammed Y Khanji, Marinos Koulouroudias, Redha Boubertakh, Filip Zemrak, James C. Moon |
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| Jazyk: | angličtina |
| Předmět: |
Measurement reproducibility
Medicine(all) medicine.medical_specialty Radiological and Ultrasound Technology business.industry Splanchnic Circulation Blood flow Adenosine Adenosine receptor Internal medicine Poster Presentation East london medicine Cardiology Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine business Perfusion medicine.drug Angiology |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance |
| ISSN: | 1532-429X |
| DOI: | 10.1186/1532-429x-17-s1-p122 |
| Popis: | Background The sensitivity of adenosine stress perfusion CMR scans is reduced by inadequate response to adenosine. This can be due to a variety of environmental and pharmacological factors, including recent caffeine intake. Manisty et al (2014) observed that splenic blood flow is attenuated by adenosine, as the splanchnic circulation contains vasoconstrictor adenosine receptors, and may provide a simple visual marker of adequate pharmacological stress. The aim of this study was to validate measurement of splenic switch-off (SSO) in both a quantitative and qualitative manner and examine its prevalence in an East London tertiary cardiac centre. |
| Databáze: | OpenAIRE |
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