Assisted reproductive technologies (ART) and placental abnormalities
| Autor: | Anna Fuchs, Elizabeth Cochrane, Gregory W. Kirschen, Devon Soucier, David Garry, Christine E Pando |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Reproductive Techniques Assisted Placenta Placenta Previa Reproductive technology Comorbidity Umbilical cord Risk Assessment Ultrasonography Prenatal Body Mass Index Umbilical Cord 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Abruptio Placentae 030304 developmental biology Retrospective Studies 0303 health sciences Fetus 030219 obstetrics & reproductive medicine Placental abruption business.industry Obstetrics Infant Newborn Pregnancy Outcome Obstetrics and Gynecology medicine.disease Delivery Obstetric United States Placenta previa Parity medicine.anatomical_structure Pediatrics Perinatology and Child Health Velamentous cord insertion Gestation Female business |
| Zdroj: | Journal of perinatal medicineReferences. 48(8) |
| ISSN: | 1619-3997 |
| Popis: | Objectives Assisted reproductive technologies (ART) may be associated with placental abnormalities including placenta previa, umbilical cord abnormalities, and placental abruption. Our study evaluates the relationship between ART and placental abnormalities compared with spontaneously conceived controls. Methods An IRB-approved cohort study was conducted including women who delivered between January 2013 and December 2018. We excluded delivery prior to 23 weeks and known fetal anomalies. Patients were matched with controls (2:1) for parity, age, and mode of delivery. Controls were women who had spontaneously conceived and delivered immediately preceding and following the index delivery. The primary outcome was placental abnormalities found on both antenatal ultrasound and pathology in ART gestations compared with spontaneously conceived gestations. Results There were 120 ART pregnancies and 240 matched control pregnancies identified. The groups were similar for parity, BMI, comorbidities, number of multiples, mode of delivery, and female newborns. The ART group had a higher maternal age (37.1±5 y vs. 30.0±5 y; p Conclusions ART is associated with increased rate of placental abnormalities, including abnormal umbilical cord insertion and increased rates of adherent placentation. This information may be beneficial in planning and surveillance in patients with ART pregnancies. |
| Databáze: | OpenAIRE |
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