Very early tissue coverage after drug-eluting stent implantation: an optical coherence tomography study

Autor: Yoshio Kobayashi, Masayuki Takahara, Kazumasa Sugimoto, Hideki Kitahara, Takashi Nakayama, Takeshi Nishi, Yoshihide Fujimoto, Tomoaki Miyayama, Keiichiro Miura
Rok vydání: 2016
Předmět:
Staged Percutaneous Coronary Intervention
Male
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Stent coverage
Coronary Artery Disease
030204 cardiovascular system & hematology
Prosthesis Design
03 medical and health sciences
0302 clinical medicine
Percutaneous Coronary Intervention
Optical coherence tomography
Japan
Neointima
medicine
Humans
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
030212 general & internal medicine
Stent thrombosis
Everolimus
Prospective Studies
Cardiac imaging
Aged
Sirolimus
medicine.diagnostic_test
business.industry
Coronary Thrombosis
Stent
Cardiovascular Agents
Drug-Eluting Stents
Middle Aged
equipment and supplies
Coronary Vessels
surgical procedures
operative
Treatment Outcome
Drug-eluting stent
Female
Radiology
Cardiology and Cardiovascular Medicine
Early phase
business
Platelet Aggregation Inhibitors
Tomography
Optical Coherence
Zdroj: The international journal of cardiovascular imaging. 33(1)
ISSN: 1875-8312
Popis: The aim of this study was to evaluate neointimal coverage in the very early phase after second-generation drug-eluting stent (DES) implantation using optical coherence tomography (OCT). Patients who underwent staged percutaneous coronary intervention within 30 days after DES implantation were enrolled. OCT was performed to observe DES previously implanted. The median time interval from implantation to OCT examination was 21.5 days. A total of 10,625 struts of 54 stents (52 everolimus-eluting stents and 2 zotarolimus-eluting stents) in 42 lesions were analyzed. Strut tissue coverage was observed in 71.1 ± 19.2 % of the struts, malapposed struts in 2.56 ± 3.37 %, strut tissue coverage at the side branch orifice in 10.6 ± 17.2 %, and struts with protrusion in 0.95 ± 3.46 %. Mean tissue thickness on the covered struts was 39.8 ± 14.2 µm. The percentage of stent coverage was significantly lower in the overlapping segments than in the non-overlapping segments (48.4 ± 17.5 % vs. 74.4 ± 20.2 %, P
Databáze: OpenAIRE
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