Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey
Autor: | Philip Scheltens, Henrike Wolf, Daniela Bertens, R. C. Petersen, Ineke van Rossum, Pieter Jelle Visser, Patrick G. Kehoe, Flavio Nobili, Michael T. Heneka, José Luis Molinuevo, Alexandre de Mendonça, Stephanie J.B. Vos, Jacub Hort |
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Přispěvatelé: | Psychiatrie & Neuropsychologie, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Neurology, Amsterdam Neuroscience - Neurodegeneration |
Rok vydání: | 2019 |
Předmět: |
Male
0301 basic medicine Pediatrics Neurology Disease GUIDELINES lcsh:RC346-429 0302 clinical medicine Surveys and Questionnaires Survey Cognitive impairment DEMENTIA diagnosis [Alzheimer Disease] Cognition ASSOCIATION Middle Aged 3. Good health Patient management Europe ALZHEIMERS-DISEASE Female MCI MCI due to AD Prodromal AD Questionnaire medicine.medical_specialty Attitude of Health Personnel Cognitive Neuroscience BIOMARKERS Prodromal Symptoms DIAGNOSIS behavioral disciplines and activities lcsh:RC321-571 03 medical and health sciences Alzheimer Disease mental disorders MANAGEMENT medicine Humans Dementia Cognitive Dysfunction ddc:610 Clinical care lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry lcsh:Neurology. Diseases of the nervous system business.industry Research medicine.disease nervous system diseases 030104 developmental biology diagnosis [Cognitive Dysfunction] Neurology (clinical) business human activities 030217 neurology & neurosurgery Geriatric psychiatry |
Zdroj: | Alzheimer's Research & Therapy, 11(1):74. BioMed Central Ltd Bertens, D, Vos, S, Kehoe, P, Wolf, H, Nobili, F, Mendonça, A, van Rossum, I, Hort, J, Molinuevo, J L, Heneka, M, Petersen, R, Scheltens, P & Visser, P J 2019, ' Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: A European survey ', Alzheimer's Research and Therapy, vol. 11, no. 1, 74 . https://doi.org/10.1186/s13195-019-0525-9 Alzheimer's Research and Therapy, 11(1):74. BioMed Central Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019) Bertens, D, Vos, S, Kehoe, P, Wolf, H, Nobili, F, Mendonça, A, van Rossum, I, Hort, J, Molinuevo, J L, Heneka, M, Petersen, R, Scheltens, P & Visser, P J 2019, ' Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care : a European survey ', Alzheimer's Research and Therapy, vol. 11, 74 (2019) . https://doi.org/10.1186/s13195-019-0525-9 Alzheimer's Research & Therapy Alzheimer's research & therapy 11(1), 74 (2019). doi:10.1186/s13195-019-0525-9 |
ISSN: | 1758-9193 |
Popis: | Introduction The diagnosis of mild cognitive impairment (MCI) refers to cognitive impairment not meeting dementia criteria. A survey among members of the American Association of Neurology (AAN) showed that MCI was considered a useful diagnosis. Recently, research criteria have been proposed for the diagnosis of Alzheimer’s disease (AD) in MCI based on AD biomarkers (prodromal AD/MCI due to AD). The aim of this study was to investigate the attitudes of clinicians in Europe on the clinical utility of MCI and prodromal AD/MCI due to AD criteria. We also investigated whether the prodromal AD/MCI due to AD criteria impacted management of MCI patients. Methods An online survey was performed in 2015 among 102 members of the European Academy of Neurology (EAN) and the European Alzheimer’s Disease Consortium (EADC). Questions were asked on how often criteria were used, how they were operationalized, how they changed patient management, and what were considered advantages and limitations of MCI and prodromal AD/MCI due to AD. The questionnaire consisted of 47 questions scored on a Likert scale. Results Almost all respondents (92%) used the MCI diagnosis in clinical practice. Over 80% of the EAN/EADC respondents found a MCI diagnosis useful because it helped to label the cognitive problem, involve patients in planning for the future, and start risk reduction activities. These findings were similar to those reported in the AAN survey. Research criteria for prodromal AD/MCI due to AD were used by 68% of the EAN/EADC respondents. The most common reasons to use the criteria were increased certainty of diagnosis (86%), increased possibilities to provide counseling (51%), facilitation of follow-up planning (48%), start of medical intervention (49%), and response to patients’ wish for a diagnosis (41%). Over 70% of the physicians considered that a diagnosis of prodromal AD/MCI due to AD had an added value over the MCI diagnosis. Conclusions The diagnostic criteria of MCI and prodromal AD/MCI due to AD are commonly used among EAN/EADC members. The prodromal AD/MCI due to AD were considered clinically useful and impacted patient management and communication. Electronic supplementary material The online version of this article (10.1186/s13195-019-0525-9) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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