Selective abolition of Mayer waves in conscious endotoxemic rats
| Autor: | Bruno Chapuis, Christian Barrès, Claude Julien |
|---|---|
| Přispěvatelé: | Université Claude Bernard Lyon 1 (UCBL), Université de Lyon |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Sympathetic Nervous System Baroreceptor Consciousness [SDV]Life Sciences [q-bio] Stimulation Baroreflex Kidney Rats Sprague-Dawley 03 medical and health sciences Cellular and Molecular Neuroscience Vascular reactivity 0302 clinical medicine Internal medicine Animals Medicine baroreflex Mayer waves renal sympathetic nerve activity Sympathetic tone Endocrine and Autonomic Systems business.industry Sympathetic nerve activity Endotoxemia Rats Disease Models Animal Blood pressure Cardiology Neurology (clinical) arterial pressure business 030217 neurology & neurosurgery |
| Zdroj: | Autonomic Neuroscience: Basic and Clinical Autonomic Neuroscience: Basic and Clinical, Elsevier, 2020, 226, pp.102673. ⟨10.1016/j.autneu.2020.102673⟩ |
| ISSN: | 1566-0702 1872-7484 |
| Popis: | International audience; The relation between vascular sympathetic tone and the amplitude of arterial pressure (AP) Mayer waves was examined by analyzing 60-min recordings of AP and renal sympathetic nerve activity (RSNA) obtained in conscious rats before and after lipopolysaccharide administration, which results in strong sympathoexcitation. Mayer waves completely disappeared together with accompanying oscillations of RSNA. Meanwhile, the gain of the sympathetic baroreceptor reflex was increased, thus suggesting that abolition of Mayer waves resulted from the previously reported reduction of vascular reactivity to α-adrenoceptor stimulation. In conclusion, the amplitude of Mayer waves cannot be used indiscriminately as an index of vascular sympathetic tone. |
| Databáze: | OpenAIRE |
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