Daptomycin efficacy in the central nervous system of a patient with disseminated methicillin-resistant Staphylococcus aureus infection: a case report
Autor: | Nicola Petrosillo, Stefania Stefani, Elisabetta Grilli, Antonino Di Caro, Giulia V. Stazi, Taschia Bertuccio, Alessandro Capone, Floriana Campanile, Fabrizio Taglietti |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
Medicine(all)
medicine.medical_specialty business.industry Nosocomial pathogens Central nervous system lcsh:R lcsh:Medicine Case Report General Medicine biochemical phenomena metabolism and nutrition medicine.disease_cause bacterial infections and mycoses Methicillin-resistant Staphylococcus aureus medicine.anatomical_structure Staphylococcus aureus Medicine Daptomycin business Intensive care medicine Pathogen medicine.drug |
Zdroj: | Journal of Medical Case Reports, Vol 6, Iss 1, p 264 (2012) Journal of Medical Case Reports |
Popis: | Introduction Staphylococcus aureus has emerged as a major nosocomial pathogen in the last decades and also represents the second most common pathogen isolated from patients in outpatient settings. Although methicillin-resistant S.aureus infections were traditionally limited to hospitals, community-associated cases of methicillin-resistant S.aureus infections have been reported. In our case, we observed an unexpected event during treatment. Case presentation A 60-year-old Caucasian man developed fever and multiple muscle and brain abscesses caused by Panton-Valentine leukocidin-negative community-associated methicillin-resistant S. aureus. Conclusion Although our patient was given antimicrobials active against the isolated methicillin-resistant S. aureus strain, it was only after the introduction of daptomycin that his skin, soft tissue and muscle lesions and also brain manifestations improved. |
Databáze: | OpenAIRE |
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