Daptomycin efficacy in the central nervous system of a patient with disseminated methicillin-resistant Staphylococcus aureus infection: a case report

Autor: Nicola Petrosillo, Stefania Stefani, Elisabetta Grilli, Antonino Di Caro, Giulia V. Stazi, Taschia Bertuccio, Alessandro Capone, Floriana Campanile, Fabrizio Taglietti
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 6, Iss 1, p 264 (2012)
Journal of Medical Case Reports
Popis: Introduction Staphylococcus aureus has emerged as a major nosocomial pathogen in the last decades and also represents the second most common pathogen isolated from patients in outpatient settings. Although methicillin-resistant S.aureus infections were traditionally limited to hospitals, community-associated cases of methicillin-resistant S.aureus infections have been reported. In our case, we observed an unexpected event during treatment. Case presentation A 60-year-old Caucasian man developed fever and multiple muscle and brain abscesses caused by Panton-Valentine leukocidin-negative community-associated methicillin-resistant S. aureus. Conclusion Although our patient was given antimicrobials active against the isolated methicillin-resistant S. aureus strain, it was only after the introduction of daptomycin that his skin, soft tissue and muscle lesions and also brain manifestations improved.
Databáze: OpenAIRE