Outcome of multiple-wire localization for larger breast cancers: do multiple wires translate into additional imaging, biopsies, and recurrences?
| Autor: | Laurie Kirstein, Sara H. Javid, Kevin S. Hughes, Barbara L. Smith, Colleen Murphy, Jennifer Rusby, Alphonse G. Taghian, Michelle C. Specht, Stuart R. Lipsitz, Richard D. Moore, Elizabeth A. Rafferty |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Biopsy medicine.medical_treatment Mammary gland Breast Neoplasms Mastectomy Segmental Metastasis Breast cancer medicine Humans Neoplasm Metastasis Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Lumpectomy Cancer Anatomical pathology General Medicine Middle Aged medicine.disease Surgery Radiography Treatment Outcome medicine.anatomical_structure Female Breast disease Radiology Neoplasm Recurrence Local business |
| Zdroj: | The American Journal of Surgery. 198:368-372 |
| ISSN: | 0002-9610 |
| Popis: | Background Breast conservation is possible in breast cancer patients whose mammographic lesions are large enough to require multiple localizing wires for excision. Methods A retrospective review of 112 patients who underwent multiple-wire and 160 controls who underwent single-wire lumpectomy for breast cancer. Rates of in-breast recurrence, metastasis, and additional imaging and biopsy procedures were calculated. Results The median follow-up was 24 months. One multiple-wire and 2 single-wire patients developed in-breast recurrences ( P = .84). No distant metastases developed among the multiple-wire patients. Additional follow-up imaging was obtained in 29% of multiple-wire and 22% of single-wire cases ( P = .1). Seven (6%) of the multiple-wire and 11 (6%) of the single-wire cases underwent biopsy ( P = .94). Conclusions We found no increased risk of early local recurrence, metastasis, or additional imaging or biopsies in patients requiring multiple-wire localization for lumpectomy. Breast conservation should be considered a safe option even for patients with mammographically extensive lesions. |
| Databáze: | OpenAIRE |
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