Cabazitaxel in castration resistant prostate cancer with brain metastases: 3 case reports

Autor: Tania Policastro, Piera Federico, Giuseppe Di Lorenzo, Livio Puglia, Sabino De Placido, Pasquale Rescigno, Michela Izzo, Davide Bosso, Carlo Buonerba
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Popis: Prostate cancer is the most common non-cutaneous malignancy for men. The skeleton is the most common metastatic site but, following an improvement in survival, metastases in uncommon sites are being found more frequently in clinical practice, especially brain metastases. Despite the new drugs now available for metastatic castration resistant prostate cancer, no clinical evidence exists about their effectiveness on brain metastases. We describe the clinical history of 3 patients treated with cabazitaxel plus whole brain radiotherapy. These case reports demonstrate that cabazitaxel is highly active and well tolerated in brain metastases.
Databáze: OpenAIRE