Challenges in diagnosis and understanding of natural history of polycystic ovary syndrome

Autor:	Anju E. Joham, Terhi Piltonen, Marla E. Lujan, Sylvia Kiconco, Chau Thien Tay
Rok vydání:	2022
Předmět:	Adult Endocrinology Adolescent Endocrinology Diabetes and Metabolism Androgens Humans Female Genetic Predisposition to Disease Obesity Adiposity Polycystic Ovary Syndrome
Zdroj:	Clinical Endocrinology. 97:165-173
ISSN:	1365-2265 0300-0664
DOI:	10.1111/cen.14757
Popis:	Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting 8%-13% of reproductive-aged women. The aetiology of the syndrome is complex, with genetic susceptibility, androgen exposure in early life and adiposity related dysfunction leading to perturbance in hypothalamic-ovarian function. PCOS clinical features are heterogeneous, with manifestations arising even in early adolescence, developing into multisystem reproductive, metabolic and psychological manifestations in adulthood. In this review, we will discuss challenges in the diagnosis of PCOS and understanding of the natural history of PCOS.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33f05328ebd7481cc2291894de6888e https://doi.org/10.1111/cen.14757 Zobrazit plný text záznamu Plný text