Narrowband ultraviolet B phototherapy improves quality of life of psoriasis and atopic dermatitis patients up to 3 months : Results from an observational multicenter study
| Autor: | Rafael Pasternack, Riikka Pastila, Hannu Kautiainen, Liisa Väkevä, Adrienn Joensuu, Sirkka Niemelä, Lasse Ylianttila, Meri Lauha, Erna Snellman, Toni Karppinen, Mari Grönroos, Anna Hannuksela‐Svahn, Minna Soronen, Anna Hjerppe |
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| Přispěvatelé: | Staff Services, HUS Inflammation Center, Department of Dermatology, Allergology and Venereology, Clinicum, Department of General Practice and Primary Health Care, HUS Helsinki and Uusimaa Hospital District, HYKS erva, Päijät-Häme Welfare Consortium, Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology, Tampere University |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Self-Administrated PASI HELIOTHERAPY Scoring of Atopic Dermatitis 030207 dermatology & venereal diseases 0302 clinical medicine Psoriasis Area and Severity Index S3-GUIDELINES Quality of life Surveys and Questionnaires Immunology and Allergy 030212 general & internal medicine SCORAD INDEX medicine.diagnostic_test Sisätaudit - Internal medicine General Medicine Atopic dermatitis Dermatology Life Quality Index Middle Aged 3. Good health PHOTOCHEMOTHERAPY Costs and Cost Analysis Female Ultraviolet Therapy Adult medicine.medical_specialty Adolescent Biolääketieteet - Biomedicine Immunology Dermatology Dermatitis Atopic 03 medical and health sciences Psoriasis medicine Humans Radiology Nuclear Medicine and imaging Aged business.industry Pruritus UVB PHOTOTHERAPY medicine.disease EFFICACY body regions Patient-Oriented SCORAD SEVERITY Multicenter study 3121 General medicine internal medicine and other clinical medicine Quality of Life Observational study business |
| Popis: | Background/Purpose Narrowband UVB phototherapy is a common treatment modality in psoriasis and atopic dermatitis, but evidence of its actual effect in clinical setting is sparse. Our aim was to assess the effectiveness and costs of narrowband UVB phototherapy in psoriasis and atopic dermatitis in clinical setting. Methods We observed 207 psoriasis patients and 144 atopic dermatitis patients in eight centers. SAPASI, PO-SCORAD, and VAS measures were used at baseline, at the end, and 3 months after the narrowband UVB phototherapy course. Quality of life was measured using Dermatology Life Quality Index (DLQI), and costs were assessed using a questionnaire. Results In both psoriasis and atopic dermatitis, the DLQI and Self-Administrated PASI (SAPASI)/Patient-Oriented SCORAD (PO-SCORAD) improved significantly and the results remained improved for at least 3 months in both groups. Alleviation of pruritus correlated with better quality of life in both patient groups. We reported slight redness and burning side effects which were due to lack of MED testing. Self-administered tools proved to be useful in evaluating pruritus and severity of the disease in psoriasis and atopic dermatitis. Mean patient costs were 310 euro and 21 hours of time, and mean costs for the healthcare provider were 810 euro. Conclusion In psoriasis, narrowband UVB is a very efficient treatment in clinical setting, whereas in atopic dermatitis, more studies are needed to determine the best dosage. |
| Databáze: | OpenAIRE |
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