Adenocarcinoma Developing at the Level of a Chronic Perianal Fistula by Cell Implantation from a Proximal Rectal Cancer

Autor:	Lucian Sorin Andrei, Oana Rizea, Adriana Andrei, Silviu Ciurea, Gabriel Becheanu, Niculina Ioana Luca, Radu Sorin Popisteanu
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	medicine.medical_specialty Medicine (General) business.industry Colorectal cancer Cell General Medicine perianal fistula medicine.disease Gastroenterology medicine.anatomical_structure R5-920 Perianal fistula Internal medicine medicine Adenocarcinoma metastasis Medicine business rectal cancer
Zdroj:	Modern Medicine, Vol 27, Iss 2, Pp 133-138 (2020)
ISSN:	2360-2473 1223-0472
Popis:	Anorectal adenocarcinoma is a very rare complication which can occur during the long-lasting evolution of perianal fi stulas (PAF), chronic inflammation being the main predisposing factor incriminated for malignant evolution. Moreover, in rare cases (only 28 being published until now), adenocarcinoma developing at the level of a perianal fistula may occur by migration of tumoral cells originating from a rectal cancer into the granulation tissue of the fistula. We present the case of a patient with a rectal adenocarcinoma that has metastasized to a perianal fistula, in evolution for 7 years. Clinical suspicion of malignant seeding at the site of the fistula has been confirmed by immunohistochemical studies.
Databáze:	OpenAIRE
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