Risk factors for frontal fibrosing alopecia: A case-control study in a multiracial population
| Autor: | Paulo Müller Ramos, Leopoldo Duailibe Nogueira Santos, Bruna Duque-Estrada, Fabiane Mulinari-Brenner, Giselle Martins Pinto, Rodrigo Pirmez, Débora Cadore de Farias, Hélio Amante Miot, Alessandra Anzai, Leonardo Spagnol Abraham, Daniel Fernandes Melo |
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| Přispěvatelé: | Universidade Estadual Paulista (UNESP), Universidade de São Paulo (USP), Santa Casa de Misericórdia do Rio de Janeiro, Universidade Federal de Santa Catarina (UFSC), Universidade Estadual do Rio de Janeiro, Universidade Federal do Paraná (UFPR), Santa Casa Misericórdia, Universidade de Brasília (UnB), Santa Casa de São Paulo |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population frontal fibrosing alopecia Dermatology tobacco 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Recall bias medicine sunscreens risk factors Hair straightening education education.field_of_study integumentary system business.industry Frontal fibrosing alopecia Case-control study Environmental exposure Odds ratio medicine.disease Rosacea 030220 oncology & carcinogenesis business case-control |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Made available in DSpace on 2022-05-01T03:29:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01 Background: Frontal fibrosing alopecia (FFA) is a chronic cicatricial alopecia with unknown etiology and a worldwide rising incidence. Objective: The objective of this study was to evaluate the association of FFA with demographic and exposure factors in a Brazilian multiracial population. Methods: A multicenter case-control study was conducted in 11 referral centers throughout Brazil. The study was a case-control study that prospectively recruited 902 participants (451 patients with FFA and 451 sex-matched control individuals). Study participants completed a thorough questionnaire comprising variables grouped as baseline demographics, environmental exposure, diet, hormonal factors, allergies, and hair and skin care. Results: When adjusted by sex, age, menopause, and skin color, FFA was associated with hair straightening with formalin (odds ratio [OR], 3.18), use of ordinary (nondermatologic) facial soap (OR, 2.09) and facial moisturizer (OR, 1.99), thyroid disorders (OR, 1.69), and rosacea (OR, 2.08). Smokers (OR, 0.33) and users of antiresidue/clarifying shampoo (OR, 0.35) presented a negative association with FFA. There was no association with the use of sunscreen. Limitations: Recall bias. Conclusions: The association with moisturizers, ordinary facial soap, and hair straightening with formalin and the negative association with antiresidue/clarifying shampoo reinforce the possibility of an exogenous particle triggering FFA. Universidade Estadual Paulista Universidade de São Paulo Santa Casa de Misericórdia do Rio de Janeiro Universidade Federal de Santa Catarina Universidade Estadual do Rio de Janeiro Universidade Federal do Paraná Santa Casa Misericórdia Universidade de Brasília Santa Casa de São Paulo Universidade Estadual Paulista |
| Databáze: | OpenAIRE |
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