Is Inspiratory Muscle Weakness a Determinant of Endurance Exercise Tolerance During NIV-Supported Exercise in Patients With COPD?
| Autor: | Gabriel Victor Guimarães Rapello, Rodrigo Koch, Paulo de Tarso Müller |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Weakness medicine.medical_specialty Maximal Respiratory Pressures medicine.medical_treatment Pressure support ventilation Pulmonary Disease Chronic Obstructive Random Allocation 03 medical and health sciences 0302 clinical medicine Heart Rate Endurance training Internal medicine Heart rate medicine Humans Aerobic exercise Single-Blind Method Prospective Studies 030212 general & internal medicine Continuous positive airway pressure Exercise physiology Interactive Ventilatory Support Exercise Aged COPD Cross-Over Studies Exercise Tolerance Muscle Weakness Noninvasive Ventilation Continuous Positive Airway Pressure business.industry Rehabilitation Middle Aged medicine.disease Respiratory Muscles respiratory tract diseases Oxygen Dyspnea 030228 respiratory system Exercise Test Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiopulmonary Rehabilitation and Prevention. 38:E9-E11 |
| ISSN: | 1932-7501 |
| DOI: | 10.1097/hcr.0000000000000329 |
| Popis: | Previous research has reported that inspiratory muscle weakness is critical to decreased exercise tolerance and exercise tolerance improves with 10 cmH2O pressure support ventilation in patients with chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate the effects of proportional assist ventilation (PAV) and continuous positive airway pressure (CPAP) compared with sham on exercise tolerance in patients with and without inspiratory muscle weakness.In a prospective design, 12 of 54 patients were eligible after clinical and comprehensive lung function evaluation, including maximum inspiratory pressure (MIP) measurement. Using baseline measures, participants were divided into 2 age-matched groups that differed in regard to MIP (Group 1, MIP60 cmH2O, and Group 2, MIP ≥60 cmH2O). Each participant performed 3 constant work rate tests with noninvasive support (PAV, CPAP, sham) in random order on different days at 80% of maximal incremental power.During the endurance tests, heart rate, peripheral oxygen saturation (SpO2), dyspnea perception scale, and exercise tolerance were measured. There were no significant differences between groups for heart rate, SpO2, dyspnea perception, or exercise tolerance during PAV, CPAP, or sham-supported exercise (P.05 for all).In this small representative group of patients with COPD, inspiratory muscle weakness was not a determining factor of performance during CPAP or PAV-supported aerobic exercise. |
| Databáze: | OpenAIRE |
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