The pulsatile secretion of bioactive luteinising hormone in normal adult men
| Autor: | J. Alan Talbor, R. Stuart, C. Rodger, Steven M. Shalet, Malcolm D. Littley, William R. Robertson |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Periodicity Time Factors medicine.drug_class Endocrinology Diabetes and Metabolism Pulsatile flow Radioimmunoassay Biology Luteinising hormone Mice Endocrinology Internal medicine medicine Animals Humans Testosterone Pulse (signal processing) Pulse duration Leydig Cells General Medicine Luteinizing Hormone Biological Assay Gonadotropin Pulsatile secretion Follicle Stimulating Hormone |
| Zdroj: | Acta endocrinologica. 122(5) |
| ISSN: | 0001-5598 |
| Popis: | We have studied bioactive and immunoreactive LH pulsatility in 11 normal men. The temporal relationship of plasma LH, testosterone, and FSH were also investigated. Blood samples were taken at 10-minute intervals for 6 h and bioactive LH levels were determined using an in vitro mouse Leydig cell bioassay. Testosterone, LH and FSH were determined by standard radioimmunoassay. Twenty-two bioactive LH pulses were detected (amplitude 8.5±4.9 IU/l, mean±sd) with a frequency of 2±0.8/6 h compared with only 18 immunoreactive LH pulses (amplitude of 3.6±1.8 IU/l) and a frequency of 1.6±0.5/6 h. Bioactive:immunoreactive LH ratios increased (p |
| Databáze: | OpenAIRE |
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