Growth after conversion to alternate-day corticosteroids in children with renal transplants: a single-center study
| Autor: | J T Flynn, H. Jorge Baluarte, Martin S. Polinsky, Bruce A. Kaiser, Stephen P. Dunn, Manuel Mochon, Jo Ann Palmer |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Adolescent Urology Renal function Growth Kidney Function Tests Drug Administration Schedule Nephropathy Prednisone Internal medicine Humans Transplantation Homologous Medicine Child Kidney transplantation Kidney business.industry Graft Survival Bone age medicine.disease Kidney Transplantation Surgery Transplantation medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Cyclosporine Kidney Failure Chronic Female business medicine.drug |
| Zdroj: | Pediatric Nephrology. 8:320-325 |
| ISSN: | 1432-198X 0931-041X |
| Popis: | During the 1980s all children with growth potential and stable/adequate renal function at 6–9 months after kidney transplantation underwent conversion to alternate-day corticosteroids in an attempt to maximize growth. Conversion was attempted in 79 of 160 children who received allografts during this decade and was considered successful if they remained on alternate-day prednisone for more than 1 year, with a calculated creatinine clearance of at least 75% of the pre-conversion baseline value. Conversion succeeded in 55 children but failed in 24. Growth was markedly improved among those successfully converted when compared with the failure group, as measured by standard deviation score for growth velocity based on chronological age (+0.94±1.58 vs. −0.86±1.53,P |
| Databáze: | OpenAIRE |
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