Epileptic seizures with reversible lesions in bilateral frontoparietal lobes: A case report and literature review
| Autor: | Guangming Wang, Weihong Lin, Lichao Sun, Zhanpeng Zhu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Epilepsy Frontal Lobe Remission Spontaneous Case Reports Electroencephalography Biochemistry 03 medical and health sciences Epilepsy 0302 clinical medicine Seizures Parietal Lobe medicine case report Humans In patient Oxcarbazepine medicine.diagnostic_test Epileptogenic lesion business.industry Biochemistry (medical) Magnetic resonance imaging Cell Biology General Medicine medicine.disease Frontal Lobe 030104 developmental biology Radiology Abnormality business Sharp wave 030217 neurology & neurosurgery MRI periictal MRI abnormalities medicine.drug |
| Zdroj: | The Journal of International Medical Research |
| ISSN: | 1473-2300 0300-0605 |
| Popis: | Magnetic resonance imaging (MRI) is recommended for patients with epileptic seizures to rule out an underlying focal lesion. However, the radiological characteristics of epilepsy are not well elucidated. Transient periictal MRI abnormality (TPMA) refers to reversible MRI signal changes observed in epileptic patients. A 32-year-old man presented with a 2-week history of epileptic seizures, which initially manifested as focal aware seizures and progressed to a generalized tonic-clonic seizure on the third day. Electroencephalography showed sharp waves, sharp and slow wave complexes, and irregular δ waves over bilateral temporal lobes. After admission, brain MRI showed abnormal signals in the bilateral frontoparietal lobes. He was administered oral oxcarbazepine (75 mg twice daily). During follow-up he was seizure-free; the abnormal MRI signals persisted at 2 weeks, but were completely resolved at 4 months. The possibility of TPMA should be considered in patients with epileptic disorders, and differentiated from a potential epileptogenic lesion. |
| Databáze: | OpenAIRE |
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