Management of Ureteral Obstruction in Advanced Testicular Tumor with Lymph Node Metastasis
| Autor: | Eiichiro Takaoka, Atsushi Ikeda, Koji Kawai, Jun Miyazaki, Takehiro Oikawa, Takahiro Kojima, Satoshi Ando, Takayuki Yoshino, Hiroyuki Nishiyama, Takahiro Suetomi, Hiromu Inai, Tomokazu Kimura |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Adolescent medicine.medical_treatment Retroperitoneal Lymph Node Urology Antineoplastic Agents Kidney urologic and male genital diseases Nephrectomy Metastasis Young Adult Retroperitoneal lymph node dissection Ureter Testicular Neoplasms medicine Humans Radiology Nuclear Medicine and imaging Retroperitoneal Space Ureteric stent Aged Retrospective Studies urogenital system business.industry General Medicine Seminoma Middle Aged medicine.disease Chemotherapy regimen female genital diseases and pregnancy complications Surgery surgical procedures operative medicine.anatomical_structure Oncology Lymphatic Metastasis Lymph Node Excision Female Stents Germinoma business Ureteral Obstruction |
| Zdroj: | Japanese Journal of Clinical Oncology. 42:748-752 |
| ISSN: | 1465-3621 0368-2811 |
| Popis: | OBJECTIVE: Ureteral obstruction is one of the complications of testicular tumor with retroperitoneal lymph node metastasis that requires ureteral stenting for management. We elucidated the clinical courses of ureteral obstructions and changes in renal functions in patients with indwelling ureteral stenting. METHODS: The medical records of 56 patients who were treated for metastatic testicular tumors by chemotherapy at a single institute between 2002 and 2010 were retrospectively reviewed. RESULTS: Among 56 patients, 12 patients needed ureteral stenting before chemotherapy. The proportion of patients requiring ureteral stenting was significantly higher in seminoma than non-seminoma (47 and 12%, respectively, P < 0.05). The ureteral stent was removed after chemotherapy or retroperitoneal lymph node dissection in all patients, except for one patient who died of cancer during chemotherapy. At retroperitoneal lymph node dissection, ureters were spared in three patients, a partial ureterectomy was needed in one patient, and no case underwent adjunctive nephrectomy. These 11 patients presented no local and distant recurrence at median follow-up of 44 months. Ureteral stenting increased the estimated glomerular filtration rate to more than 60 ml/min before chemotherapy in all patients, but it decreased to |
| Databáze: | OpenAIRE |
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