Cloudy corneas as an initial presentation of multiple myeloma
Autor: | Stephen J. Morgan, Haifa A. Madi, Priyanka Sharma, Richard Bonshek |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
medicine.medical_specialty
Pathology genetic structures medicine.medical_treatment Case Report immune system diseases Ophthalmology hemic and lymphatic diseases vortex keratopathy Biopsy medicine Cornea verticillata Multiple myeloma crystalline keratopathy medicine.diagnostic_test business.industry corneal crystals Corneal crystals Phacoemulsification medicine.disease eye diseases multiple myeloma Cloudy corneas Histopathology sense organs Presentation (obstetrics) medicine.symptom business |
Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
ISSN: | 1177-5483 1177-5467 |
Popis: | Summary: We report a case of previously unsuspected myeloma, presenting with cornea verticillata due to intracorneal paraprotein deposition. History: An 85-year-old female presented via her optician with a 4-month history of cloudy vision. She had undergone an uneventful bilateral phacoemulsification surgery 7 years earlier. Extensive spiraling corneal epithelial opacification was noted on slit-lamp examination. On further investigation, she was found to have a previously unsuspected low-grade multiple myeloma. We established the nature of the corneal deposits with corneal epithelial biopsy histopathology and electron microscopy. It is very rare for multiple myeloma to present in this fashion. Ophthalmologists should be aware that such a presentation may rarely be due to systemic multiple myeloma. Keywords: corneal crystals, multiple myeloma, crystalline keratopathy, vortex keratopathy Introduction Corneal deposits of various types have been described in multiple myeloma, monoclonal gammopathy, and essential cryoglobulinemia. |
Databáze: | OpenAIRE |
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