Ethanol reduces asymmetry of visual rCBF responses
| Autor: | Peter E. Wendt, Ingmar Rosén, Georg Stenberg, David H. Ingvar, Jarl Risberg |
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| Předmět: |
Adult
Male medicine.medical_specialty Cerebral vasodilatation Cortical asymmetry Left posterior Body weight Functional Laterality chemistry.chemical_compound Reference Values Cortex (anatomy) Internal medicine medicine Premovement neuronal activity Humans Analysis of Variance Ethanol Osmolar Concentration medicine.anatomical_structure Neurology chemistry Regional Blood Flow Anesthesia Cerebrovascular Circulation Cardiology Neurology (clinical) Occipital Lobe Cardiology and Cardiovascular Medicine Psychology Photic Stimulation |
| Zdroj: | Scopus-Elsevier Europe PubMed Central |
| Popis: | Visual regional CBF (rCBF) responses were measured in 10 healthy male subjects before and after an ethanol dose of 1 g/kg body weight. This dose induces well-established cerebral vasodilatation. However, significant bilateral occipital increases were found in both conditions. Apparently, the coupling between neuronal activity and rCBF is preserved following ethanol. The occipital and posterior parietal flow increases were, however, larger on the right than the left side in the sober state. During inebriation the asymmetry disappeared, possibly representing a more undifferentiated processing of visual information. We propose that ethanol causes a reduced inhibition of the left posterior cortex and a reduction of right-hemisphere information processing. |
| Databáze: | OpenAIRE |
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