Dedifferentiation: the return road to repair the intestinal epithelium
| Autor: | Ye-Guang Chen, Yuan Liu, Xiaochen Xiong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
lcsh:R5-920
0303 health sciences Cell Crypt Cell Biology Biology Intestinal epithelium Research Highlight Cell biology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure lcsh:Biology (General) medicine Stem cell Progenitor cell lcsh:Medicine (General) lcsh:QH301-705.5 030217 neurology & neurosurgery 030304 developmental biology Developmental Biology Stem Cell Recovery |
| Zdroj: | Cell Regeneration Cell Regeneration, Vol 9, Iss 1, Pp 1-3 (2020) |
| ISSN: | 2045-9769 |
| Popis: | In the March 5 issue of Cell Stem Cell, (Murata K et al. Cell Stem Cell. 26(377–390):e376 2020) reported that intestinal stem cell recovery after injury is principally through Ascl2-dependent dedifferentiation of absorptive and secretory precursors in mice. This study provides evidence for robust regenerative capability of the intestinal epithelium via dedifferentiation of absorptive and secretory progenitors in the crypt. |
| Databáze: | OpenAIRE |
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