Approach to Intestinal Failure in Children

Autor: Valeria C. Cohran, Danielle Wendel, Conrad R. Cole
Rok vydání: 2021
Předmět:
Zdroj: Current gastroenterology reportsPapers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance. 23(6)
ISSN: 1534-312X
Popis: Pediatric intestinal failure is a complex condition requiring specialized care to prevent potential complications. In this article, we review the available evidence supporting recent advances in care for children with intestinal failure. Multidisciplinary intestinal rehabilitation teams utilize medical and surgical management techniques to help patients achieve enteral autonomy (EA) while preventing and treating the complications associated with intestinal failure. Recent advances in lipid management strategies, minimization of intestinal failure associated liver disease, prevention of central line-associated blood stream infections, and loss of access, as well as development of promising new hormone analogue therapy have allowed promotion of intestinal adaptation. These advances have decreased the need for intestinal transplant. There have been recent advances in the care of children with intestinal failure decreasing morbidity, mortality, and need for intestinal transplantation. The most promising new therapies involve replacement of enteroendocrine hormones.
Databáze: OpenAIRE