Health-related quality of life in women and men with type 2 diabetes: a comparison across treatment groups
| Autor: | Peter Reitmeir, Alexander Kluttig, Teresa Tamayo, Ute Ellert, Klaus Berger, K.H. Ladwig, M Schunk, Christa Meisinger, Sabine Schipf, Wolfgang Rathmann, Rolf Holle, Henry Völzke, K. H. Greiser, Hanne Neuhauser, Grit Müller |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Gerontology Endocrinology Diabetes and Metabolism medicine.medical_treatment Comorbidity Type 2 diabetes Treatment and control groups Endocrinology Quality of life Stress Physiological Germany Diabetes mellitus Diet Diabetic Linear regression Prevalence Internal Medicine medicine Humans Hypoglycemic Agents Insulin In patient Aged Psychiatric Status Rating Scales Health related quality of life Sex Characteristics business.industry Middle Aged medicine.disease Combined Modality Therapy Health Surveys humanities Cross-Sectional Studies Diabetes Mellitus Type 2 Linear Models Quality of Life Drug Therapy Combination Female business Stress Psychological |
| Zdroj: | Journal of Diabetes and its Complications. 29:203-211 |
| ISSN: | 1056-8727 |
| Popis: | This study compares health-related quality of life (HRQL) in patients with type 2 diabetes (T2DM) across treatment groups and explores gender differences.Four regional surveys (KORA, CARLA, SHIP, DHS) and a national survey (GNHIES98) were pooled at individual level. HRQL was assessed with the SF-12/-36v1. Linear regression models were used to assess the effect of T2DM by treatment type (no medication; oral; oral/insulin combination; insulin) on the physical (PCS-12) and mental summary score (MCS-12) and the SF-6D, controlling for age, sex, study and covariates. We also performed an explanatory analysis of single items.PCS-12 scores and treatment type were associated (P-value 0.006), with lowest values for insulin treatment (-4.44 vs. oral; -4.41 vs. combination). MCS-12 scores were associated with treatment type and gender (P-value0.012), with lower scores for women undergoing oral (-4.25 vs. men) and combination treatment (-6.99 vs. men). Similar results were observed for SF-6D utilities and single items, related to mental health, social functioning, vitality and role limitation (emotional). Comorbidities were predictors of lower PCS-12 and SF-6D scores.T2DM treatment impacts differently on physical and mental HRQL and on women and men. Further studies of gender-specific perceptions of T2DM treatment regimens are needed. |
| Databáze: | OpenAIRE |
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