Studies on the vascular drainage system of the hamster buccal pouch

Autor: D. Antoniadis, J. L. Giunta, Joel Schwartz
Rok vydání: 1985
Předmět:
Zdroj: Journal of Oral Pathology and Medicine. 14:263-267
ISSN: 1600-0714
0904-2512
DOI: 10.1111/j.1600-0714.1985.tb00490.x
Popis: Because some investigators feel that the hamster buccal pouch is an immune privileged site with no lymphatic drainage, this study was done to demonstrate and further elucidate a drainage system from the pouch to the cervical nodes. Eight hamsters were injected with india ink, submucosally in the right pouch. Dissections at one or 2 days revealed ink in macrophages in the right submandibular nodes at 2 days. Histologically, the ink was noted within macrophages which aggregated around blood vessels. No lymph vessels were noted in the pouch. Six hamsters were injected with fluorochrome-labelled latex microspheres. At 2 and at 4 days the microspheres were noted in both the pouches and the ipsilateral submandibular nodes. The results indicate there is a delayed lymphatic drainage from cheek pouches to the submandibular nodes mediated by macrophages.
Databáze: OpenAIRE