The Prevalence of Measles Antibody in Human Immunodeficiency Virus‐Infected Patients in Northern California
| Autor: | Stanley C. Deresinski, Gabriela Arias, Carol A. Kemper, Mona Gangar, Carol Kane |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Adolescent Opportunistic infection HIV Infections Antibodies Viral Measles California Measles virus Morbillivirus Acquired immunodeficiency syndrome (AIDS) Seroepidemiologic Studies medicine Humans Immunology and Allergy Seroprevalence Risk factor Aged biology business.industry Middle Aged biology.organism_classification medicine.disease Infectious Diseases Immunology Female Serostatus business |
| Zdroj: | The Journal of Infectious Diseases. 178:1177-1180 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1086/515679 |
| Popis: | The seroprevalence of measles (rubeola) antibody in 619 human immunodeficiency virus (HIV)-infected adults was determined by a standard ELISA. Risk factors for a lack of antibody and presumed susceptibility to measles were examined. Whereas overall, 9.8% of patients (60) were found to lack antibody, 17.8% of those born within the United States in 1957 or later were antibody-negative. Multivariate analysis showed that absence of measles antibody was significantly associated with younger age (born in 1957 or later) (odds ratio [OR], 8.15; 95% confidence interval [CI], 3.7-21.5; P < .0001) and birth within the United States (OR, 4.72; 95% CI, 1.7-19.7; P = .0045). Neither minority status, stage of HIV infection, CD4 cell count, nor a history of opportunistic infection bore any relationship to the presence of antibody. While progression of HIV disease does not affect measles serostatus, younger HIV-infected patients, especially those born in the United States in 1957 or later, are at the greatest risk for measles. |
| Databáze: | OpenAIRE |
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