Construction of a dual-responsive dual-drug delivery platform based on the hybrids of mesoporous silica, sodium hyaluronate, chitosan and oxidized sodium carboxymethyl cellulose

Autor:	Dan, Shao, Qiang, Gao, Yanshan, Sheng, Shangji, Li, Yong, Kong
Rok vydání:	2022
Předmět:	Chitosan Drug Carriers Sodium General Medicine Hydrogen-Ion Concentration Silicon Dioxide Biochemistry Drug Delivery Systems Structural Biology Carboxymethylcellulose Sodium Nanoparticles Hyaluronic Acid Porosity Molecular Biology
Zdroj:	International Journal of Biological Macromolecules. 202:37-45
ISSN:	0141-8130
DOI:	10.1016/j.ijbiomac.2022.01.033
Popis:	An intelligent drug delivery platform based on the hybrids of mesoporous silica nanoparticles (MSN), sodium hyaluronate (HA), chitosan (CS) and oxidized sodium carboxymethyl cellulose (oxCMC) is developed, which can be used for dual-responsive dual-drug delivery. Hydrophilic cytarabine (Cyt) is first loaded into the mesopores of the aminated MSN (NH
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ecb8e37dba5d2b3d3af66792afb4b4 https://doi.org/10.1016/j.ijbiomac.2022.01.033 Zobrazit plný text záznamu Full Text from ScienceDirect