Predictors of long‐term renal allograft survival after second kidney transplantation
| Autor: | Ponnusamy Mohan, Kieran J. Breen, Richard E. Power, Dilly M. Little, John O’Kelly, Eoin MacCraith, Atakelet A Ferede, Niall F. Davis, Patrick O'Kelly, G. P. Smyth, James C. Forde |
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| Rok vydání: | 2020 |
| Předmět: |
Graft Rejection
medicine.medical_specialty Urology 030230 surgery Kidney Kidney transplant 03 medical and health sciences 0302 clinical medicine Secondary outcome Risk Factors Humans Medicine Kidney transplantation Retrospective Studies Transplantation business.industry Incidence (epidemiology) Graft Survival Perioperative Allografts medicine.disease Kidney Transplantation Delayed Graft Function surgical procedures operative medicine.anatomical_structure Renal allograft 030211 gastroenterology & hepatology business |
| Zdroj: | Clinical Transplantation. 34 |
| ISSN: | 1399-0012 0902-0063 |
| Popis: | INTRODUCTION Few studies investigate significant perioperative predictors for long-term renal allograft survival after second kidney transplant (SKT). We compared long-term survival following SKT with primary kidney transplant and determined predictors of renal allograft failure after SKT. METHODS Outcomes of all primary or second kidney transplant recipients at a national kidney transplant center between 1993 and 2017 were reviewed. The primary outcomes measurements were renal allograft survival for both first and second kidney transplants. Secondary outcome measurements were incidence of delayed graft function (DGF), incidence of acute rejection (AR), and predictors for renal allograft survival in SKT recipients. RESULTS In total, there were 392 SKTs and 2748 primary kidney transplants performed between 1993 and 2017. The 1-, 5-, and 10-year death-censored graft survival for deceased-donor recipients was 95.3%, 88.7%, and 78.2% for primary kidney transplant and 94.9%, 87.1%, and 74.9% for SKT (P = .0288). Survival of primary renal allograft |
| Databáze: | OpenAIRE |
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