Sulfadoxine-pyrimethamine susceptibilities and analysis of the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum isolates from Côte d'Ivoire
| Autor: | Joseph Allico Djaman, A. Mazabraud, Leonardo K. Basco |
|---|---|
| Přispěvatelé: | Développement et évolution (DE), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Centre de génétique moléculaire (CGM), Centre National de la Recherche Scientifique (CNRS), Mécanismes adaptatifs : des organismes aux communautés (MAOAC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC) |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_treatment
DHPS MESH: Tetrahydrofolate Dehydrogenase 0302 clinical medicine MESH: Animals Malaria Falciparum MESH: Dihydropteroate Synthase [SDV.BDD]Life Sciences [q-bio]/Development Biology MESH: Plasmodium falciparum Antibacterial agent 0303 health sciences biology MESH: Malaria Falciparum MESH: Infant 3. Good health Drug Combinations Pyrimethamine Infectious Diseases [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology Child Preschool medicine.drug Sulfadoxine MESH: Pyrimethamine MESH: Cote d'Ivoire Plasmodium falciparum 030231 tropical medicine Antimalarials 03 medical and health sciences parasitic diseases medicine Animals Humans Dihydrofolate synthase MESH: Drug Combinations Dihydropteroate Synthase MESH: Humans 030306 microbiology MESH: Child Preschool Infant biology.organism_classification Virology MESH: Antimalarials Sulfadoxine/pyrimethamine Tetrahydrofolate Dehydrogenase Cote d'Ivoire biology.protein Parasitology Dihydropteroate synthase MESH: Sulfadoxine |
| Zdroj: | Annals of Tropical Medicine and Parasitology Annals of Tropical Medicine and Parasitology, 2007, 101 (2), pp.103-12. ⟨10.1179/136485907X154584⟩ Annals of Tropical Medicine and Parasitology, Maney Publishing, 2007, 101 (2), pp.103-12. ⟨10.1179/136485907X154584⟩ |
| ISSN: | 0003-4983 1364-8594 |
| DOI: | 10.1179/136485907X154584⟩ |
| Popis: | International audience; Over a 2-year study period, three methods [a test of therapeutic efficacy, an in-vitro assay, and sequencing of the parasites' dihydrofolate-reductase (dhfr) and dihydropteroate-synthase (dhps) genes] were used to monitor sulfadoxine-pyrimethamine (SP) resistance in the Plasmodium falciparum strains infecting young children near Abidjan, the largest city in C?d'Ivoire. Overall, 118 children aged |
| Databáze: | OpenAIRE |
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