Helicobacter pylori and nutrition: a bidirectional communication
| Autor: | Costanza Pira, Andrea Devecchi, U. Aimasso, Antonella De Francesco, Valentina D'Onofrio, F.D. Merlo, Chiara D'Eusebio |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Malabsorption
Atrophic gastritis Endocrinology Diabetes and Metabolism media_common.quotation_subject medicine.medical_treatment Nutritional Status Cobalamin Helicobacter Infections chemistry.chemical_compound Internal Medicine Humans Medicine Pathogen media_common Nutrition and Dietetics Helicobacter pylori biology business.industry Vitamin E Gastroenterology Appetite medicine.disease biology.organism_classification chemistry Immunology Ghrelin business |
| Zdroj: | Minerva Gastroenterologica e Dietologica. 65 |
| ISSN: | 1827-1642 1121-421X |
| DOI: | 10.23736/s1121-421x.19.02568-6 |
| Popis: | Helicobacter pylori (HP) is a gram-negative flagellated pathogen acid-resistant bacterium; it belongs to the order Campylobacterales that is wide spread all over the world, infecting more than 50% of the world population. HP infection is etiologically associated with non-atrophic and atrophic gastritis, peptic ulcer and with 3 to 6-fold increased relative risk for developing gastric adenocarcinoma and mucosa-associated lymphoid tissue (MA LT) lymphoma. For this reason HP is recognized by the World Health Organization as a Class I human carcinogen. In the last years a lot of studies clarified the role of this pathogen in nutrition and metabolism; particularly, it has been shown that it is able to induce malabsorption of several nutrients like iron, cobalamin, vitamin C and vitamin E, with strong consequences on nutritional status. Interesting, this bacterium is able to produce different biological effects on hormones like ghrelin and leptin controlling both appetite and growth, mostly depending on the time of acquisition of the infection and of its treatment. In this review, the authors focused their attention on nutritional effects of HP infection and particularly on the role that diet, food, plants and specific nutrients can play in its treatment, considering that HP eradication rates, with standard triple-therapy, have fallen to a low level in the last years. |
| Databáze: | OpenAIRE |
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