Biomarkers of fungal infection: Expert opinion on the current situation

Autor: José Garnacho-Montero, Patricia Muñoz, Maurizio Sanguinetti, Miguel Salavert, Julio Rodríguez, Emilio Bouza, Benito Almirante
Přispěvatelé: UAM. Departamento de Medicina Preventiva y Salud Pública y Microbiología, Instituto de Investigación Sanitaria Hospital Universitario de La Paz (IdiPAZ)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Review
Cuidados intensivos
Bronchoalveolar Lavage
Mannans
Aspergilosis invasora
CAGTA
0302 clinical medicine
1-3ß-D-Glucano
Medicine
Fluorescent Antibody Technique
Indirect
Glucans
Cuidados críticos
Candida
Negativity effect
General Medicine
Invasive candidiasis
Mannan
Intensive Care Units
Anti-Manano
Aspergillus
biomarcadores fúngicos
Galactomanano
Microbiology (medical)
Antifungal
medicine.medical_specialty
Critical Care
medicine.drug_class
Medicina
030106 microbiology
Combined use
T2Candida
Sensitivity and Specificity
03 medical and health sciences
Invasive fungal infections
Intensive care
Aspergillosis
Humans
Antifungal stewardship
False Positive Reactions
Intensive care medicine
Antibodies
Fungal
Pharmacology
Candidiasis invasora
Fungal biomarkers
business.industry
Intensive Care
Galactose
Candidemia
030208 emergency & critical care medicine
medicine.disease
1-3 beta-D-Glucan
política de antifúngicos
Infección fúngica invasora
1-3ß-D-Glucan
Spain
Expert opinion
Galactomannan
Manano
Invasive aspergillosis
Treatment decision making
business
Biomarkers
Anti-Mannan
Zdroj: Revista Española de Quimioterapia
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Europe PubMed Central
Biblos-e Archivo. Repositorio Institucional de la UAM
Universidad Camilo José Cela (UCJC)
ISSN: 0214-3429
Popis: The introduction of non-culture-based diagnostic techniques is revolutionizing the world of microbiological diagnosis and infection assessment. Fungi are no exception, and the introduction of biomarkers has opened up enormous expectations for better management of these entities. Biomarkers are diverse, their targets are also diverse and their evaluation has been done preferably in an individualized use and with deficient designs. Less is known about the value of the combined use of biomarkers and the impact of the negativity of two or more biomarkers on antifungal treatment decisions has been poorly studied. Given the paucity of prospective, randomized and definitive studies, we have convened experts from different fields, with an interest in invasive fungal infections, to answer some questions about the current relevant use of fungal biomarkers. This document summarizes the answers of these experts to the different questions.
Databáze: OpenAIRE
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