Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays
| Autor: | Lesedi Lebogang, Kosin Teeparuksapun, Bo Mattiasson, Martin Hedström |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Immunoassay
Chromatography medicine.diagnostic_test Chemistry Bioengineering Nanotechnology 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Sensitivity and Specificity 01 natural sciences Antibodies Orders of magnitude (mass) 0104 chemical sciences medicine Capacitive biosensor Sensitivity (control systems) 0210 nano-technology Biotechnology |
| Zdroj: | Trends in Biotechnology. 35:1021-1024 |
| ISSN: | 0167-7799 |
| DOI: | 10.1016/j.tibtech.2017.06.001 |
| Popis: | It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using 'normal' antibodies (Abs). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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